Envíe este artículo por correo electrónico 
Enfoque multidisciplinario del manejo del trastorno por atracón y la Diabetes Mellitus Tipo
Resumen
El trastorno por atracón y la diabetes mellitus tipo 2 representan una intersección crítica en la salud pública, donde la coexistencia de ambas condiciones no solo complica el manejo de la diabetes, sino que también incrementa el riesgo de complicaciones. La identificación de factores de riesgo comunes y el impacto del trastorno alimentario en el manejo de la diabetes son esenciales para desarrollar intervenciones efectivas. Dado el creciente número de casos de diabetes, resulta urgente integrar el tratamiento de los trastornos de la conducta alimentaria en los planes de manejo de la diabetes, adoptando un enfoque holístico que considere tanto los aspectos físicos como psicológicos. El trastorno por atracón está caracterizado por episodios recurrentes de consumo excesivo de alimentos, sin conductas compensatorias. El trastorno se asocia con un alto grado de comorbilidad, especialmente con la obesidad y enfermedades como hipertensión y diabetes. La prevalencia del trastorno por atracón es notablemente mayor en pacientes con obesidad mórbida y diabetes tipo 2. Un enfoque multidisciplinario, que incluya endocrinólogos, psiquiatras y nutricionistas, es fundamental para optimizar los tratamientos y mejorar la calidad de vida de estos pacientes. Se requieren más investigaciones para abordar esta compleja comorbilidad y mejorar las intervenciones terapéuticas disponibles. El objetivo de esta revisión fue establecer el enfoque multidisciplinario del manejo del trastorno por atracón y la diabetes tipo 2.
Recibido: 25 de Noviembre de 2024.
Aceptado: 18 de Mayo de 2025.
Palabras clave
Texto completo:
PDFReferencias
Khan TA, Field D, Chen V, Ahmad S, Mejia SB, Kahleová H, Rahelić D, Salas-Salvadó J, Leiter LA, Uusitupa M, Kendall CWC, Sievenpiper JL. Combination of multiple low-risk lifestyle behaviors and incident type 2 diabetes: A systematic review and dose-response meta-analysis of prospective cohort studies. Diabetes Care. 2023; 46: 643-56. [PubMed][Google Scholar]
ElSayed NA, Aleppo G, Aroda VR, Bannuru RR, Brown FM, Bruemmer D, Collins BS, Hilliard ME, Isaacs D, Johnson EL, Kahan S, Khunti K, Leon J, Lyons SK, Perry ML, Prahalad P, Pratley RE, Seley JJ, Stanton RC, Gabbay RA, on behalf of the American Diabetes Association. Obesity and weight management for the prevention and treatment of type 2 diabetes: Standards of care in diabetes-2023. Diabetes Care. 2023; 46: S128-S39. [PubMed] [Google
Scholar]
Chesney E, Goodwin GM, Fazel S. Risks of all-cause and suicide mortality in mental disorders: a meta-review. World Psychiatry. 2014; 13: 153-160.
[PubMed] [Google Scholar]
Lewis YD, Bergner L, Steinberg H, Bentley J, Himmerich H. Pharmacological studies in eating disorders: A historical review. Nutrients. 2024; 16: 594. [PubMed] [Google Scholar]
IsHak WW, Mirocha J, Dang J, Vanle B, Metrikin B, Tessema K, Danovitch I. Quality of life and functioning impairments across psychiatric disorders in adults presenting for outpatient psychiatric evaluation and treatment. Psychiatr Res Clin Pract. 2024; 6: 68-77. [PubMed] [Google Scholar]
Walker ER, McGee RE, Druss BG. Mortality in mental disorders and global disease burden implications: a systematic review and meta-analysis. JAMA
Psychiatry. 2015; 72: 334-41. [PubMed] [Google Scholar]
Wassenaar E, Friedman J, Mehler PS. medical complications of binge eating disorder. Psychiatr Clin North Am. 2019; 42: 275-286. [PubMed] [Google Scholar]
Citrome L. Binge eating disorder revisited: what's new, what's different, what's next. CNS Spectr. 2019; 24: 4-13. [PubMed] [Google Scholar]
Udo T, Grilo CM. Prevalence and Correlates of DSM-5-Defined eating disorders in a nationally representative sample of U.S. Adults. Biol Psychiatry.
; 84: 345-54. [PubMed] [Google Scholar]
Micali N, Martini MG, Thomas JJ, Eddy KT, Kothari R, Russell E, Bulik CM, Treasure J. Lifetime and 12-month prevalence of eating disorders amongst women in midlife: a population-based study of diagnoses and risk factors. BMC Med. 2017; 15: 12. [PubMed] [Google Scholar]
Giel KE, Bulik CM, Fernandez-Aranda F, Hay P, Keski-Rahkonen A, Schag K, Schmidt U, Zipfel S. Binge eating disorder. Nat Rev Dis Primers. 2022; 8: 16. [PubMed] [Google Scholar]
Keski-Rahkonen A. Epidemiology of binge eating disorder: prevalence, course, comorbidity, and risk factors. Curr Opin Psychiatry. 2021; 34: 525-31. [PubMed] [Google Scholar]
Galmiche M, Déchelotte P, Lambert G, Tavolacci MP. Prevalence of eating disorders over the 2000-2018 period: a systematic literature review. Am J Clin Nutr. 2019; 109: 1402-13. [PubMed] [Google Scholar]
Duncan AE, Ziobrowski HN, Nicol G. The prevalence of past 12-month and lifetime DSM-IV eating disorders by BMI Category in US men and women. Eur Eat Disord Rev. 2017; 25: 165-71. [PubMed] [Google Scholar]
Alhuwaydi AM, Alqahtani AM, Alsadun RS, Alruwaili OS, Thirunavukkarasu A, Abdel-Salam DM, Alanazi YSA, Al-Huwaidi IAM, Alhuwaydi RMA. Assessment of binge eating behavior, body shape concerns, and associated factors among female adolescents of northern Saudi Arabia: A Cross-Sectional Study.
Nutrients. 2024; 16: 3082. [PubMed] [Google Scholar]
McCuen-Wurst C, Ruggieri M, Allison KC. Disordered eating and obesity: associations between binge-eating disorder, night-eating syndrome, and
weight-related comorbidities. Ann N Y Acad Sci. 2018; 1411: 96-105. [PubMed] [Google Scholar]
Zhang J, Abbasi O, Malevanchik L, Mohan N, Denicola R, Tarangelo N, Marzio DH. Pilot study of the prevalence of binge eating disorder in non-alcoholic fatty liver disease patients. Ann Gastroenterol. 2017; 30: 664-9. [PubMed] [Google Scholar]
Williams GA, Hawkins MAW, Duncan J, Rummell CM, Perkins S, Crowther JH. Maladaptive eating behavior assessment among bariatric surgery candidates:
Evaluation of the Eating Disorder Diagnostic Scale. Surg Obes Relat Dis. 2017; 13: 1183-8. [PubMed] [Google Scholar]
Swanson SA, Crow SJ, Le Grange D, Swendsen J, Merikangas KR. Prevalence and correlates of eating disorders in adolescents. Results from the national comorbidity survey replication adolescent supplement. Arch Gen Psychiatry. 2011; 68: 714-23. [PubMed] [Google Scholar]
Stice E, Marti CN, Rohde P. Prevalence, incidence, impairment, and course of the proposed DSM-5 eating disorder diagnoses in an 8-year prospective
community study of young women J Abnorm Psychol. 2013; 122: 445-57. [PubMed] [Google Scholar]
Abbott S, Dindol N, Tahrani AA, Piya MK. Binge eating disorder and night eating syndrome in adults with type 2 diabetes: a systematic review. J Eat Disord. 2018; 6: 36. [PubMed] [Google Scholar]
Micali N, Field AE, Treasure JL, Evans DM. Are obesity risk genes associated with binge eating in adolescence? Obesity. 2015; 23: 1729–36. [PubMed] [Google Scholar]
Qasim A, Mayhew AJ, Ehtesham S, Alyass A, Volckmar AL, Herpertz S, Hinney A, Hebebrand J, Meyre D. Gainof-function variants in the melanocortin 4 receptor gene confer susceptibility to binge eating disorder in subjects with obesity: a systematic review and meta-analysis. Obes Rev. 2019; 20: 13-21. [PubMed] [Google Scholar]
Succurro E, Segura-Garcia C, Ruffo M, Caroleo M, Rania M, Aloi M, De Fazio P, Sesti G, Arturi F. Obese patients with a binge eating disorder have an unfavorable metabolic and inflammatory profile. Medicine (Baltimore). 2015; 94: e2098. [PubMed] [Google Scholar]
Raevuori A, Suokas J, Haukka J, Gissler M, Linna M, Grainger M, Suvisaari J. Highly increased risk of type 2 diabetes in patients with binge eating disorder and bulimia nervosa. Int J Eat Disord. 2015; 48: 555-62. [PubMed] [Google Scholar]
Pacanowski CR, Linde JA, Faulconbridge LF, Coday M, Safford MM, Chen H, Yanovski SZ, Ewing LJ, Wing R, Jeffery RW; Look AHEAD Research
Group. Psychological status and weight variability over eight years: Results from Look AHEAD. Health Psychol. 2018; 37: 238-246. [PubMed] [Google Scholar]
Cremonini F, Camilleri M, Clark MM, Beebe TJ, Locke GR, Zinsmeister AR, Herrick LM, Talley NJ. Associations among binge eating behavior patterns and gastrointestinal symptoms: a populationbased study. Int J Obes (Lond). 2009; 33: 342-53. [PubMed] [Google Scholar]
Khalsa SS, Berner LA, Anderson LM. Gastrointestinal interoception in eating disorders: Charting a new path. Curr Psychiatry Rep. 2022; 24: 47-60.
[PubMed] [Google Scholar]
Thornton LM, Watson HJ, Jangmo A, Welch E, Wiklund C, von HausswolffJuhlin Y, Norring C, Herman BK, Larsson H, Bulik CM. Binge-eating disorder in the Swedish national registers: Somatic comorbidity. Int J Eat Disord. 2017; 50: 58-65. [PubMed] [Google Scholar]
Raggi A, Curone M, Bianchi Marzoli S, Chiapparini L, Ciasca P, Ciceri EF, Erbetta A, Faragò G, Leonardi M, D'Amico D. Impact of obesity and binge eating disorder on patients with idiopathic intracranial hypertension. Cephalalgia. 2017; 37: 278-83. [PubMed] [Google Scholar]
Ágh T, Kovács G, Pawaskar M, Supina D, Inotai A, Vokó Z. Epidemiology, healthrelated quality of life and economic burden of binge eating disorder: a systematic literature review. Eat Weight Disord. 2015; 20: 1-12. [PubMed] [Google Scholar]
Huisman SD, Hendrieckx C, Bot M, Pouwer F, Nefs G. Prevalence, associations and health outcomes of binge eating in adults with type 1 or type
diabetes: Results from Diabetes MILES - The Netherlands. Diabet Med. 2023; 40: e14953. [PubMed] [Google Scholar]
Claro AE, Palanza C, Mazza M, Corsello A, Rizzi A, Tartaglione L, de Waure C, Marano G, Piciollo S, Muti Schuenemann GEU, Rigoni M, Muti P, Pontecorvi A, Janiri L, Sani G, Pitocco D. Evaluation of the prevalence of the most common psychiatric disorders in patients with type 2 diabetes mellitus using the patient health questionnaire: results of the crosssectional "DIA2PSI" study. Acta Diabetol. 2023; 60: 247-255. [PubMed] [Google
Scholar]
Papelbaum M, de Oliveira Moreira R, Coutinho WF, Kupfer R, Freitas S, Raggio Luz R, Appolinario JC. Does binge-eating matter for glycemic control in type 2 diabetes patients? J Eat Disord. 2019; 7: 30. [PubMed] [Google Scholar]
Herpertz S, Wagener R, Albus C, Kocnar M, Wagner R, Best F, Schleppinghoff BS, Filz HP, Förster K, Thomas W, Mann K, Köhle K, Senf W. Diabetes mellitus and eating disorders: a multicenter study on the comorbidity of the two diseases. J Psychosom Res. 1998; 44: 503-515. [PubMed] [Google Scholar]
Shakeri Z, Mardali F, Azizabadi Farahani M, Alemrajabi M, Mottaghi A. Comparison of eating disorders and eating behaviors in adults with and
without type 2 diabetes prior to bariatric surgery. J Eat Disord. 2022; 10: 107. [PubMed] [Google Scholar]
Alonso J, de Jonge P, Lim CC, AguilarGaxiola S, Bruffaerts R, Caldas-deAlmeida JM, Liu Z, O'Neill S, Stein DJ, Viana MC, Al-Hamzawi AO, Angermeyer
MC, Borges G, Ciutan M, de Girolamo G, Fiestas F, Haro JM, Hu C, Kessler RC, Lépine JP, Levinson D, Nakamura Y, Posada-Villa J, Wojtyniak BJ, Scott KM. Association between mental disorders and subsequent adult onset asthma. J Psychiatr Res. 2014; 59: 179-88. [PubMed] [Google Scholar]
Hudson JI, Lalonde JK, Coit CE, Tsuang MT, McElroy SL, Crow SJ, Bulik CM, Hudson MS, Yanovski JA, Rosenthal NR, Pope HG Jr. Longitudinal study of the diagnosis of components of the metabolic syndrome in individuals with binge-eating disorder. Am J Clin Nutr. 2010; 91: 1568- 73. [PubMed] [Google Scholar]
Nieto-Martínez R, González-Rivas JP, Medina-Inojosa JR, Florez H. Are eating disorders risk factors for type 2 diabetes? A systematic review and meta-analysis. Curr Diab Rep. 2017; 17: 138. [PubMed] [Google Scholar]
Crow S, Kendall D, Praus B, Thuras P. Binge eating and other psychopathology in patients with type II diabetes mellitus. Int J Eat Disord. 2001; 30: 222-6. [PubMed] [Google Scholar]
Nicolau J, Simó R, Sanchís P, Ayala L, Fortuny R, Zubillaga I, Masmiquel L. Eating disorders are frequent among type 2 diabetic patients and are associated with worse metabolic and psychological outcomes: results from a cross-sectional study in primary and secondary care settings. Acta Diabetol. 2015; 52: 1037-44. [PubMed] [Google Scholar]
Stahel P, Sud SK, Lee SJ, Jackson T, Urbach DR, Okrainec A, Allard JP, Bassett AS, Paterson AD, Sockalingam S, Dash S. Phenotypic and genetic
analysis of an adult cohort with extreme obesity. Int J Obes (Lond). 2019; 43: 2057-65. [PubMed] [Google Scholar]
Friborg O, Martinussen M, Kaiser S, Øvergård KT, Martinsen EW, Schmierer P, Rosenvinge JH. Personality disorders in eating disorder not otherwise
specified and binge eating disorder: a meta-analysis of comorbidity studies. J Nerv Ment Dis. 2014; 202: 119-25. [PubMed] [Google Scholar]
Grilo CM, White MA, Masheb RM. DSM-IV psychiatric disorder comorbidity and its correlates in binge eating disorder. Int J Eat Disord. 2009;
: 228-34. [PubMed] [Google Scholar]
Thiebaut S, Godart N, Radon L, Courtet P, Guillaume S. Crossed prevalence results between subtypes of eating disorder and bipolar disorder: A
systematic review of the literature. Encephale. 2019; 45: 60-73. [PubMed] [Google Scholar]
Baek JH, Kim K, Hong JP, Cho MJ, Fava M, Mischoulon D, Chang SM, Kim JY, Cho H, Jeon HJ. Binge eating, trauma, and suicide attempt in community
adults with major depressive disorder. PLoS One. 2018; 13: e0198192. [PubMed] [Google Scholar]
Lydecker JA, Grilo CM. Psychiatric comorbidity as predictor and moderator of binge-eating disorder treatment outcomes: an analysis of aggregated randomized controlled trials. Psychol Med. 2021: 1-9. [PubMed] [Google Scholar]
Barakat S, McLean SA, Bryant E, Le A, Marks P; National Eating Disorder Research Consortium; Touyz S, Maguire S. Risk factors for eating disorders: findings from a rapid review. J Eat Disord. 2023; 11: 8. [PubMed] [Google Scholar]
Westwood H, Kerr-Gaffney J, Stahl D, Tchanturia K. Alexithymia in eating disorders: Systematic review and meta-analyses of studies using the
Toronto Alexithymia Scale. J Psychosom Res. 2017; 99: 66-81. [PubMed] [Google Scholar]
De Chouly De Lenclave MB, Florequin C, Bailly D. Obesity, alexithymia, psychopathology and binge eating: a comparative study of 40 obese patients
and 32 controls. Encephale. 2001; 27: 343-50. [PubMed] [Google Scholar]
Pinna F, Sanna L, Carpiniello B. Alexithymia in eating disorders: therapeutic implications. Psychol Res Behav Manag. 2014; 8: 1-15. [PubMed]
[Google Scholar]
Brunault P, Rabemampianina I, Apfeldorfer G, Ballon N, Couet C, Réveillère C, Gaillard P, El-Hage W. The Dutch Eating Behavior Questionnaire:
Further psychometric validation and clinical implications of the French version in normal weight and obese persons. Presse Med. 2015; 44: e363-e472.
[PubMed] [Google Scholar]
Burton P, Smit HJ, Lightowler HJ. The influence of restrained and external eating patterns on overeating. Appetite. 2007; 49: 191-7. [PubMed] [Google Scholar]
Benbaibeche H, Saidi H, Bounihi A, Koceir EA. Emotional and external eating styles associated with obesity. J Eat Disord. 2023; 11: 67. [PubMed] [Google Scholar]
Van Strien T, Herman CP, Verheijden MW. Eating style, overeating and weight gain. A prospective 2-year follow-up study in a representative Dutch sample. Appetite. 2012; 59: 782-9. [PubMed] [Google Scholar]
van Strien T, Herman CP, Verheijden MW. Eating style, overeating, and overweight in a representative Dutch sample. Does external eating play a role? Appetite. 2009; 52: 380-7. [PubMed] [Google Scholar]
van de Laar FA, van de Lisdonk EH, Lucassen PL, Stafleu A, Mulder J, van den Hoogen HJ, Rutten GE, van Weel C. Eating behaviour and adherence to diet in patients with Type 2 diabetes mellitus. Diabet Med. 2006; 23: 788-94. [PubMed] [Google Scholar]
Koller OG, Andrade TFCS, Machado ABC, Polet JP, Riboldi BP, Rodrigues CCR, de Almeida JC. Exploring the interplay between emotional attitudes towards diabetes, eating behaviour and glycaemic control in patients with type 2 diabetes mellitus. Public Health Nutr. 2024; 27: e237. [PubMed] [Google Scholar]
Wysocki M, Mizera M, Karpińska I, Ptaszkiewicz K, Małczak P, PisarskaAdamczyk M, Kania M, Major P. Analysis of changes in glucose and lipid
metabolism in patients with clinically severe obesity and type 2 diabetes mellitus undergoing laparoscopic sleeve gastrectomy-prospective observational study. Obes Surg. 2024; 34: 467-78. [PubMed] [Google Scholar]
Pinaquy S, Chabrol H, Simon C, Louvet JP, Barbe P. Emotional eating, alexithymia, and binge-eating disorder in obese women. Obes Res. 2003; 11: 195-201. [PubMed] [Google Scholar]
Ricca V, Castellini G, Lo Sauro C, Ravaldi C, Lapi F, Mannucci E, Rotella CM, Faravelli C. Correlations between binge eating and
emotional eating in a sample of overweight subjects. Appetite. 2009; 53: 418-21. [PubMed] [Google Scholar]
62. Haedt-Matt AA, Keel PK, Racine SE, Burt SA, Hu JY, Boker S, Neale M, Klump KL. Do emotional eating urges regulate affect? Concurrent and prospective associations and implications for risk models of binge eating. Int J Eat Disord. 2014; 47: 874-7. [PubMed] [Google Scholar]
Javaras KN, Laird NM, ReichbornKjennerud T, Bulik CM, Pope HG Jr, Hudson JI. Familiality and heritability of binge eating disorder: results of a casecontrol family study and a twin study. Int J Eat Disord. 2008; 41: 174-9. [PubMed] [Google Scholar]
Thornton LM, Mazzeo SE, Bulik CM. The heritability of eating disorders: methods and current findings. Curr Top Behav Neurosci. 2011; 6: 141-56. [PubMed] [Google Scholar]
Manfredi L, Accoto A, Couyoumdjian A, Conversi D. A systematic review of genetic polymorphisms associated with binge eating disorder. Nutrients. 2021; 13: 848. [PubMed] [Google Scholar]
Burstein D, Griffen TC, Therrien K, Bendl J, Venkatesh S, Dong P, Modabbernia A, Zeng B, Mathur D, Hoffman G, Sysko R, Hildebrandt T, Voloudakis G, Roussos P. Genome-wide analysis of a modelderived binge eating disorder phenotype identifies risk loci and implicates iron metabolism. Nat Genet. 2023; 55: 1462- 70. [PubMed] [Google Scholar]
Koren R, Munn-Chernoff MA, Duncan AE, Bucholz KK, Madden PA, Heath AC, Agrawal A. Is the relationship between binge eating episodes and personality attributable to genetic factors? Twin Res Hum Genet. 2014; 17: 65-71. [PubMed] [Google Scholar]
Agüera Z, Lozano-Madrid M, Mallorquí-Bagué N, Jiménez-Murcia S, Menchón JM, Fernández-Aranda F. A review of binge eating disorder and
obesity. Neuropsychiatr. 2021; 35: 57- 67. [PubMed] [Google Scholar]
Herman A, Bajaka A. The role of the intestinal microbiota in eating disorders - bulimia nervosa and binge eating disorder. Psychiatry Res. 2021;
: 113923. [PubMed] [Google Scholar]
Depósito Legal: ppi201102ME3935 - ISSN: 2477-9369.
Copyright ©2012 ULA Todos los derechos reservados
Todos los documentos publicados en esta revista se distribuyen bajo una
Licencia Creative Commons Atribución -No Comercial- Compartir Igual 4.0 Internacional.
Por lo que el envío, procesamiento y publicación de artículos en la revista es totalmente gratuito.